This document is part of a series, funded by the European Commission and produced by the UN Environment World Conservation Monitoring Centre, supported by UN Environment, which aims to evaluate the applications of area-based management approaches to the achievement of the Sustainable Development Goals. An area-based (or spatial) management approach enables the application of management measures to a specific geospatial area to achieve a desired policy outcome. In particular, this report identifies ways in which practitioners and decision-makers can apply Marine Spatial Planning and Integrated Coastal Zone Management approaches to support the delivery of Sustainable Development Goals 14.1 relating to the reduction of marine pollution and 14.2 relating to sustainable management and protection of marine and coastal ecosystems. Evidence of successful application of Marine Spatial Planning and Integrated Coastal Zone Management to support delivery of Targets 14.1 and 14.2 has been analysed from experiences from around the world to identify different phases that should be considered by practitioners and decision makers. A conceptual guidelines diagram is presented in Section 4, highlighting each of the phases that can be taken by practitioners. Each phase is supported by evidence extracted from indepth case studies, collected from interviews with on-the-ground practitioners and presented as full case studies in Section 5. This document serves as a guide to facilitating the effective application of Marine Spatial Planning and Integrated Coastal Zone Management approaches to support the delivery of Sustainable Development Goals 14.1 and 14.2.