Global Biodiversity Outlook-4, the mid-term review of the Strategic Plan for Biodiversity 2011-2020, provided a global assessment of progress towards the attainment of the Plan’s global biodiversity goals and associated Aichi Biodiversity Targets, but contained limited regional information. This report builds on and complements the global GBO-4 assessment. It is the second edition of the State of Biodiversity in Africa report and serves as a near mid-term review of progress towards the Strategic Plan for Biodiversity 2011-2020 for the Latin American and Caribbean region.